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Convert Database File to TERM2GENE List

dbs_to_term2genes.Rd

Reads a specified .tsv file containing information about databases, gene sets, and genes. The file should have three columns: 'DB' for database names, Geneset' for gene set identifiers, and 'Gene' for gene names. This function organizes this information into a nested list. Each top-level element corresponds to a unique database, and within each, gene sets map to lists of associated genes.

Usage

dbs_to_term2genes(databases)

Arguments

databases

A dataframe, containing the three columns DB, Geneset, and gene. This dataframe contains the databases downloaded from Enrichr with the SplineOmics package function: download_enrichr_databases.

Value

A nested list where the first level of names corresponds to database names ('DB'), the second level to gene sets ('Geneset'), and the innermost lists contain gene names ('Gene') associated with each gene set.